PRODOTTI ANTIOSSIDANTI DELLA COFATHIM-NUTRIVIT®

  • NAT® ( premix industriale) per mangimi granulato a freddo < 35C° sotto-vuoto con 24 mesi di scadenza) a base di Acidi Grassi Polinsaturi Ω3 da olio di fegato di Halibut ( o in alternativa per il mangimi destinati alla produzione di Parmigiano – Reggiano e/o Grana Padano da un complesso fito-derivato ottenuto meccanicamente a bassa temperatura ( < 35C° ) per l’estrazione della parte intracellulare di piante ricche di Vitameri Retinoidi ), di Retinolo naturale ( all’incirca 100.000.000,00 U.I. per Kg ) adsorbito su un pool di alghe marine ricchissime di Acido Grassi Polinsaturi ? 3 contenente il 15% di Omega3 ) addizionato di Vitamina D 3.
  • NAT P 5 granulé (complemento alimentare)  a base di Acidi Grassi Polinsaturi Ω3 da olio di fegato di Halibut ( o in alternativa per le vacche produttrici di latte destinato alla produzione di  Parmigiano – Reggiano e/o Grana Padano da un complesso fito-derivato ottenuto meccanicamente a bassa temperatura ( < 35C° ) della parte intracellulare di  piante ricche di Vitameri Retinoidi) contenente  all’incirca 10.000.000,00 U.I./kg ), addizionato ad elevate dosi di Vitamina E, Selenio organico e Zinco in forma chelata.
  • ANTIOXI POLIPHENOL PLUS (supplemento alimentare in emulsione liquida solubile a base di un mix di antiossidanti tipo Falvonoidi, Polifenoli e Vitamina C  naturali, di diversa origine, arricchito di  α-tocoferil-acetato Vit. E al 2,0%).
  • NAT® Selé (supplemento alimentare in emulsione solubile con il 20% di α-tocoferil-acetato Vit. E + Se ad alta assimilazione).
  • FEED CONTROL  ( complemento alimentare in farina a base di complesso fito-derivato ottenuto meccanicamente a bassa temperatura ( < 35C° ) per l’estrazione della parte intracellulare di  piante ricche di antiossidanti ( Falvonoidi, Polifenoli e Vitamina C  naturali, di diversa origine ) e piante officinali ad azione batteriostatica (es: aglio, salice, zenzero, curcuma, etc…).
  • CITRONAT® Phytodiar PIG granulé (premiscela industriale per mangimi per suinetti ) granulato a freddo  ( < 35C°) sotto-vuoto  a base di Acidi Grassi Polinsatori Ω3 da olio di fegato di Halibut adsorbiti su un pool di alghe marine α-tocoferil-acetato Vit. E e un pool di Polifenoli e Biofalvonoidi derivato da varietà plurime di Citricus , un post-biotico di ultima generazione per la regolazione del microsismo intestinale  e mix di acidificanti e  antinfiammatori naturali a base di, un mix di fito-derivati ottenuto meccanicamente a bassa temperatura ( < 35C° ) della parte intracellulare per il controllo delle forme batteriche intestinali dei suinetti.
  • CITROENAT® granulè  ( premix industriale per mangimi per suinetti) granulato a freddo ( <35C °) sotto-vuoto ( 24 mesi di scadenza ) a base di Acidi Grassi Polinsaturi Ω3 da olio di fegato di Halibut adsorbito su un pool di alghe marine, con α-tocoferil acetato 98% Vitamina E  miscelata a polifenoli e bioflavonoidi derivati da un mix di varietà di Citricus.

Per approfondimenti ed informazioni in merito agli argomenti trattati  e materiale tecnico in genere come  Etichette, Note Tecniche e Schede di sicurezza, Certificati di Qualità  ( ISO. 22000, GMP +, FCA ) e di Conformità si prega di rivolgersi direttamente all’autore per E- mail  giulio@gabaldo.com

Bibligrafia

  1. Hall J.E., Guyton A.C. Textbook of Medical Physiology. 12th ed. Saunders/Elsevier; Philadelphia, PA, USA: 2011.
  2. Gastin P.B. Energy system interaction and relative contribution during maximal exercise. Sports Med. 2001;31:725–741. doi: 10.2165/00007256-200131100-00003. [PubMed] [Cross Ref]
  3. Berg J.M., Tymoczko J.L., Stryer L. Biochemistry. 5th ed. W.H. Freeman Publisher; New York, NY, USA: 2002. Fuel choice during exercise is determined by intensity and duration of activity.
  4. Ferreira de Souza C., Fernandes L.C. Production of reactive oxygen species during the aerobic and anaerobic exercise. Rev. Bras. Cinean. Desemp. Hum. 2006;8:102–109.
  5. Baron B., Noakes T.D., Dekerle J., Moullan F., Robin S., Matran R., Pelayo P. Why does exercise terminate at the maximal lactate steady state intensity? Br. J. Sports Med. 2008;42:528–533. doi: 10.1136/bjsm.2007.040444. [PubMed] [Cross Ref]
  6. Banister E.W., Cameron B.J.C. Exercise-induced hyperammonemia: Peripheral and central effects. Int. J. Sports Med. 1990;2:S129–S142. doi: 10.1055/s-2007-1024864. [PubMed] [Cross Ref]
  7. Brouns F., Beckers E., Wagenmakers A.J., Saris W.H. Ammonia accumulation during highly intensive long-lasting cycling: Individual observations. Int. J. Sports Med. 1990;2:S78–S84. doi: 10.1055/s-2007-1024858. [PubMed] [Cross Ref]
  8. Miramonti A.A., Stout J.R., Fukuda D.H., Robinson E.H., Wang R., La Monica M.B., Hoffman J.R. Effects of 4 weeks of high-intensity interval training and ß-hydroxy-ß-methylbutyric free acid supplementation on the onset of neuromuscular fatigue. J. Strength Cond. Res. 2016;30:626–634. doi: 10.1519/JSC.0000000000001140. [PubMed] [Cross Ref]
  9. Buchheit M., Laursen P.B. High-intensity interval training, solutions to the programming puzzle. Part II: Anaerobic energy, neuromuscular load and practical applications. Sports Med. 2013;43:927–954. doi: 10.1007/s40279-013-0066-5. [PubMed] [Cross Ref]
  10. Fisher-Wellman K., Bloomer R.J. Acute exercise and oxidative stress: A 30 year history. Dyn. Med. 2009;8:1–25. doi: 10.1186/1476-5918-8-1. [PMC free article] [PubMed] [Cross Ref]
  11. Tarnopolsky M.A. Caffeine and endurance performance. Sports Med. 1994;18:109–125. doi: 10.2165/00007256-199418020-00004. [PubMed] [Cross Ref]
  12. Van der Beek E.J. Vitamin supplementation and physical exercise performance. J. Sports Sci. 1991;9:77–90. doi: 10.1080/02640419108729868. [PubMed] [Cross Ref]
  13. Chwalbiñska-Moneta J. Effect of creatine supplementation on aerobic performance and anaerobic capacity in elite rowers in the course of endurance training. Int. J. Sport Nutr. Exerc. Metab. 2003;13:173–183. doi: 10.1123/ijsnem.13.2.173. [PubMed] [Cross Ref]
  14. De Nigris F., Williams-Ignarro S., Sica V., Lerman L.O., D’Armiento F.P., Byrns R.E., Casamassimi A., Carpentiero D., Schiano C., Sumi D., et al. Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis. Cardiovasc. Res. 2007;73:414–423. doi: 10.1016/j.cardiores.2006.08.021. [PubMed] [Cross Ref]
  15. Ladurner A., Schachner D., Schueller K., Pignitter M., Heiss M.H., Somoza V., Dirsch V.M. Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species. Molecules. 2014;19:16724–16736. doi: 10.3390/molecules191016724. [PMC free article] [PubMed] [Cross Ref]
  16. Grau M., Bölck B., Bizjak D.A., Stabenow C.J.A., Bloch W. The red-vine-leaf extract AS195 increases nitric oxide synthase–dependent nitric oxide generation and decreases oxidative stress in endothelial and red blood cells. Pharmacol. Res. Perspect. 2016;4:e00213. doi: 10.1002/prp2.213. [PMC free article][PubMed] [Cross Ref]
  17. Lorenz M., Wessler S., Follmann E., Michaelis W., Dusterhoft T., Baumann G., Stangl K., Stangl V. A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation. J. Biol. Chem. 2004;279:6190–6195. doi: 10.1074/jbc.M309114200. [PubMed] [Cross Ref]
  18. World Medical Association World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013;310:2191–2194. [PubMed]
  19. Vijayananthan A., Nawawi O. The importance of good clinical practice guidelines and its role in clinical trials. Biomed. Imaging Interv. J. 2008;4:e5. doi: 10.2349/biij.4.1.e5. [PMC free article] [PubMed][Cross Ref]
  20. Inbar O., Bar-Or O., Skinners J.S. The Wingate Anaerobic Test. Human Kinetics; Champaign, IL, USA: 1996.
  21. Gül I., Gökbel H., Belviranli M., Okudan N., Büyükbas S., Başarali K. Oxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: The effect of coenzyme Q10. J. Sports Med. Phys. Fitness. 2011;51:305–312. [PubMed]
  22. Zouhal H., Rannou F., Gratas-Delamarche A., Monnier M., Bentue-Ferrer D., Delamarche P. Adrenal medulla responsiveness to the sympathetic nervous activity in sprinters and untrained subjects during a supramaximal exercise. Int. J. Sports Med. 1998;19:172–176. doi: 10.1055/s-2007-971899. [PubMed][Cross Ref]
  23. Blache D., Prost M. Free radical attack: Biological test for human resistance capability. In: Ponnamperuma C., Gehrke C.W., editors. Proceedings of the IX College Park Colloquium on Chemical Evolution: A Lunar-Based Chemical Analysis Laboratory (LBCAL 1989) NASA; Washington, DC, USA: 1992. pp. 82–98.
  24. Lesgards J.F., Durand P., Lassare M., Stocker P., Lesgards G., Lanteaume A., Prost M., Lehucher-Michel M.P. Assessment of lifestyle effects on the overall antioxidant capacity of healthy subjects. Environ. Health Perspect. 2002;110:479–487. doi: 10.1289/ehp.02110479. [PMC free article] [PubMed][Cross Ref]
  25. Kumagai J., Kawaura T., Miyazaki T., Prost M., Prost E., Watanabe M., Quentin-Leclercq J. Test for antioxidant ability by scavenging long-lived mutagenic radicals in mammalian cells and by blood test with intentional radicals: An application of gallic acid. Radiat. Phys. Chem. 2003;66:17–25. doi: 10.1016/S0969-806X(02)00288-8. [Cross Ref]
  26. Stocker P., Lesgards J.F., Vidal N., Chalier F., Prost M. ESR study of a biological assay on whole blood. Antioxidant efficiency of various vitamins. Biochim. Biophys. Acta. 2003;1621:1–8. doi: 10.1016/S0304-4165(03)00008-4. [PubMed] [Cross Ref]
  27. Caspar-Bauguil S., Maestre N., Segafredo C., Galinier A., Garcia J., Prost M., Périquet B., Pénicaud L., Salvayre R., Casteilla L. Evaluation of whole antioxidant defenses of human mononuclear cells by a new in vitro biological test: Lack of correlation between erythrocyte and mononuclear cell resistance to oxidative stress. Clin. Biochem. 2009;42:510–514. doi: 10.1016/j.clinbiochem.2008.11.014. [PubMed] [Cross Ref]
  28. Rossi R., Pastorelli G., Corino C. Application of KRL test to assess total antioxidant activity in pigs: Sensitivity to dietary antioxidants. Res. Vet. Sci. 2013;94:372–377. doi: 10.1016/j.rvsc.2012.08.005.[PubMed] [Cross Ref]
  29. Prost M. Utilisation de Générateur de Radicaux Libres dans le Domaine des Dosages Biologiques. 2,642,526. French Patent. 1989 Jan 27;
  30. Prost M. Process for the Determination by Means of Free Radicals of the Antioxidant Properties of a Living Organism or Potentially Aggressive Agents. 5,135,850 A. U.S. Patent. 1989 Jan 27;
  31. Prost M. Method for Determining the Antiradical Defense Potential and Use Thereof, in Particular in Veterinary and Human Preventive Therapeutics. 20060234329 A1. U.S. Patent. 2003 Oct 22;
  32. Driss T., Vandewalle H. The measurement of maximal (anaerobic) power output on a cycle ergometer: A critical review. BioMed Res. Int. 2013;2013:589361. doi: 10.1155/2013/589361. [PMC free article][PubMed] [Cross Ref]
  33. Johnson M.A., Sharpe G.R., Brown P.I. Inspiratory muscle training improves cycling time-trial performance and anaerobic work capacity but not critical power. Eur. J. Appl. Physiol. 2007;101:761–770. doi: 10.1007/s00421-007-0551-3. [PubMed] [Cross Ref]
  34. Cooper R., Naclerio F., Allgrove J., Jimenez A. Creatine supplementation with specific view to exercise/sports performance: An update. J. Int. Soc. Sports Nutr. 2012;9:1–11. doi: 10.1186/1550-2783-9-33. [PMC free article] [PubMed] [Cross Ref]
  35. Collomp K., Ahmaidi S., Audran M., Chanal J.L., Préfaut C. Effects of caffeine ingestion on performance and anaerobic metabolism during the Wingate Test. Int. J. Sports Med. 1991;12:439–443. doi: 10.1055/s-2007-1024710. [PubMed] [Cross Ref]
  36. Tallis J., Duncan M.J., Leddington Wright S., Eyre E.L.J., Bryant E., Langdon D., James R.S. Assessment of the ergogenic effect of caffeine supplementation on mood, anticipation timing, and muscular strength in older adults. Physiol. Rep. 2013;1:e00072. doi: 10.1002/phy2.72. [PMC free article] [PubMed][Cross Ref]
  37. Hodgson A.B., Randell R.K., Jeukendrup A.E. The metabolic and performance effects of caffeine compared to coffee during endurance exercise. PLoS ONE. 2013;8:e59561 doi: 10.1371/journal.pone.0059561. [PMC free article] [PubMed] [Cross Ref]
  38. Strait J.B., Lakatta E.G. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail. Clin. 2012;8:143–164. doi: 10.1016/j.hfc.2011.08.011. [PMC free article] [PubMed][Cross Ref]
  39. Kitzman D.W., Groban L. Exercise intolerance. Heart Fail. Clin. 2008;4:99–115. doi: 10.1016/j.hfc.2007.12.002. [PMC free article] [PubMed] [Cross Ref]
  40. Keshavarz-Motamed Z., Garcia J., Gaillard E., Capoulade R., Le Ven F., Cloutier G., Kadem L., Pibarot P. Non-invasive determination of left ventricular workload in patients with aortic stenosis using magnetic resonance imaging and doppler echocardiography. PLoS ONE. 2014;9:e86793 [PMC free article][PubMed]
  41. Vita J.A. Polyphenols and cardiovascular disease: Effects on endothelial and platelet function. Am. J. Clin. Nutr. 2005;81:292S–297S. [PubMed]
  42. Ras R.T., Zock P.L., Draijer R. Tea consumption enhances endothelial-dependent vasodilation; a meta-analysis. PLoS ONE. 2011;6:e16974 doi: 10.1371/journal.pone.0016974. [PMC free article] [PubMed][Cross Ref]
  43. Li S.H., Tian H.B., Zhao H.J., Chen L.H., Cui L.Q. The acute effects of grape polyphenols supplementation on endothelial function in adults: Meta-analyses of controlled trials. PLoS ONE. 2013;8:e69818 doi: 10.1371/journal.pone.0069818. [PMC free article] [PubMed] [Cross Ref]
  44. Kelishadi R., Gidding S.S., Hashemi M., Hashemipour M., Zakerameli A., Poursafa P. Acute and long term effects of grape and pomegranate juice consumption on endothelial dysfunction in pediatric metabolic syndrome. J. Res. Med. Sci. 2011;16:245–253. [PMC free article] [PubMed]
  45. Grassi D., Desideri G., Di Giosia P., De Feo M., Fellini E., Cheli P., Ferri L., Ferri C. Tea, flavonoids, and cardiovascular health: Endothelial protection. Am. J. Clin. Nutr. 2013;98:1660S–1666S. doi: 10.3945/ajcn.113.058313. [PubMed] [Cross Ref]
  46. Morillas-Ruiz J., Zafrilla P., Almar M., Cuevas M.J., López F.J., Abellán P., Villegas J.A., González-Gallego J. The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: Results from a placebo-controlled double-blind study in cyclists. Eur. J. Appl. Physiol. 2005;95:543–549. doi: 10.1007/s00421-005-0017-4. [PubMed] [Cross Ref]
  47. Powers S.K., De Ruisseau K.C., Quindry J., Hamilton K.L. Dietary antioxidants and exercise. J. Sports Sci. 2004;22:81–94. doi: 10.1080/0264041031000140563. [PubMed] [Cross Ref]
  48. Tauler P., Aguiló A., Fuentespina G.E. Response of blood cell antioxidant enzyme defenses to antioxidant diet supplementation and to intense exercise. Eur. J. Nutr. 2006;45:187–195. doi: 10.1007/s00394-005-0582-7. [PubMed] [Cross Ref]
  49. MacRae H.S.H., Mefferd K.M. Dietary antioxidant supplementation combined with quercetin improves cycling time trial performance. Int. J. Sport Nutr. Exerc. Met. 2006;16:405–419. doi: 10.1123/ijsnem.16.4.405. [PubMed] [Cross Ref]
  50. Bloomer R.J., Goldfarb A.H., McKenzie M.J. Oxidative stress response to aerobic exercise: Comparison of antioxidant supplements. Med. Sci. Sports Exerc. 2006;38:1098–1105. doi: 10.1249/01.mss.0000222839.51144.3e. [PubMed] [Cross Ref]

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